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Vioxx problems?

Posted by john a on 1/26/00 at 00:00 (015127)

An orthopedic foot and ankle specialist surgeon gave me some samples of vioxx, 12.5 mg to try. I took three, at 12 hour intervals, according to his direction. I had progressively worse stomach and digestion upset, so much so that I did not take another 12.5 this morning, and now feel much better. My question is could a mere three 12.5 mg tablets cause this? I thought vioxx was supposed to be much easier on the gi tract than ibuprofen, which I can tolerate for at least a few weeks. I have not seen anything bad posted here about vioxx, except that it did not work for a few people. On the contrary, most of the vioxx posts here have been raves! And indeed, it has been a wonderful pain reducer for me as well.

The one complicating factor for me is that I have also been taking 500mg(600 gdu) of bromelain two or three times a day for the last 10 days or so, a half hour or more before meals. Could the combination of vioxx and bromelain be the source of the upset stomach? (the surgeon, btw, did not know about bromelain)


Re: Vioxx problems?

wendyn on 1/26/00 at 00:00 (015130)

Although Vioxx is supposed to be better, everyone is different. I took Toradol once and could only manage 3 pills (about the same as you) it felt like it was burning a hole through my stomach. Vioxx is a very new drug - so I doubt whether or not there's a lot of information out there on whether or not it will interact with alternative medicines.



Re: Vioxx problems?

john h on 1/26/00 at 00:00 (015132)

alan my prescription is for 25mg once a day. celebrex is another one that is taken once a day. both say you can take on an empty stomach. i have had no problems with either but cannot say they have been really great at reducing pain either. due to their cost i may switch to one of the more common anti-inflamatories. vioxx and celebrex are not necessarily better at reducing inflamation but better at controlling stomach distress. some people who were taking 10 aspirin a day for arthritis now get by on 1 celebrex or vioxx tablet a day.

Re: Vioxx problems?

john a on 1/26/00 at 00:00 (015133)

Hey, alan posts a lot, but he doesn't post _every_ message! :-)

Re: Vioxx problems?

Lee H on 1/26/00 at 00:00 (015143)

Hey John, I had the exact same reaction to the Vioxx for the first 2 or 3 days. I almost quit taking it cause I was having such bad pains in my stomach but I figured I give it one more day thinking that maybe I just had a stomach bug or something. After a few days with it, it didn't bother me. The stomach pains were not immediate but came several hours after taking it. I thought it was really strange too since the main thing with Vioxx is that it doesn't upset the stomach. If the upset stomach isn't too bad, maybe you can give it a few more days, maybe your body just needs to get use to it. You could also check with your Dr. and see if anyone else has complained of this. Hope it works for you. Lee H

Re: Vioxx problems?

john h on 1/27/00 at 00:00 (015154)

i had a follow up with my doctor this morning and told him i did not know if the celebrex or vioxx either helped much. he said to try Aleve (2 in the morning and 2 before bed). as most of you know the literature out there indicates vioxx and celebrex are not any better than a lot of anti-inflamatories but are or can be easier on your stomach (not your wallet).

Re: Vioxx problems?

Lee H on 1/27/00 at 00:00 (015174)

Aleve is definately not easy on the stomach!!! I would probably just try one to begin with if you have never taken them before.

Re: Vioxx problems?

wendyn on 1/26/00 at 00:00 (015130)

Although Vioxx is supposed to be better, everyone is different. I took Toradol once and could only manage 3 pills (about the same as you) it felt like it was burning a hole through my stomach. Vioxx is a very new drug - so I doubt whether or not there's a lot of information out there on whether or not it will interact with alternative medicines.



Re: Vioxx problems?

john h on 1/26/00 at 00:00 (015132)

alan my prescription is for 25mg once a day. celebrex is another one that is taken once a day. both say you can take on an empty stomach. i have had no problems with either but cannot say they have been really great at reducing pain either. due to their cost i may switch to one of the more common anti-inflamatories. vioxx and celebrex are not necessarily better at reducing inflamation but better at controlling stomach distress. some people who were taking 10 aspirin a day for arthritis now get by on 1 celebrex or vioxx tablet a day.

Re: Vioxx problems?

john a on 1/26/00 at 00:00 (015133)

Hey, alan posts a lot, but he doesn't post _every_ message! :-)

Re: Vioxx problems?

Lee H on 1/26/00 at 00:00 (015143)

Hey John, I had the exact same reaction to the Vioxx for the first 2 or 3 days. I almost quit taking it cause I was having such bad pains in my stomach but I figured I give it one more day thinking that maybe I just had a stomach bug or something. After a few days with it, it didn't bother me. The stomach pains were not immediate but came several hours after taking it. I thought it was really strange too since the main thing with Vioxx is that it doesn't upset the stomach. If the upset stomach isn't too bad, maybe you can give it a few more days, maybe your body just needs to get use to it. You could also check with your Dr. and see if anyone else has complained of this. Hope it works for you. Lee H

Re: Vioxx problems?

john h on 1/27/00 at 00:00 (015154)

i had a follow up with my doctor this morning and told him i did not know if the celebrex or vioxx either helped much. he said to try Aleve (2 in the morning and 2 before bed). as most of you know the literature out there indicates vioxx and celebrex are not any better than a lot of anti-inflamatories but are or can be easier on your stomach (not your wallet).

Re: Vioxx problems?

Lee H on 1/27/00 at 00:00 (015174)

Aleve is definately not easy on the stomach!!! I would probably just try one to begin with if you have never taken them before.