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Nicotine promotes new blood vessel growth

Posted by BrianJ on 7/01/01 at 11:04 (051984)

I just read a medical headline stating that non-smoked nicotine promotes new blood vessel growth (see AOL's health headlines). Might this finding have applications to PF treatment -- especially post-ESWT treatment? I would be interested to know if the new blood vessel growth occurs closest to the source of nicotine infusion. If so, it might make sense to put nicotine patches on the plantar aspect of the feet. Sounds crazy, but I would appreciate any educated feedback.

Re: Nicotine promotes new blood vessel growth

wendyn on 7/01/01 at 11:14 (051989)

Hmmm Brian - this is news to me.

If a non-smoker applies a nicotine patch - there would be some profound physical side effects.

Tell you a little story...

A woman I know had recently quit smoking. She was using the strongest patch (admistered equivalent of about a pack a day nicotine.)

One night her husband (a non smoker) woke up in a cold sweat, his pulse was racing, heart was pounding - he could hardly breathe and he was itchy. Eventually he located the source of his problem - found that the patch had somehow come off the wife in the night and he had rolled onto it - sticking it to his back.

Re: Nicotine promotes new blood vessel growth

BrianJ on 7/01/01 at 11:37 (051991)

Interesting story, Wendy.

I must agree that nicotine would have side effects and would be potentially addictive. My ignorance of nicotine in particular and pharmacology in general prevents me from addressing the issue very well. Perhaps there is a way to isolate the agent that promotes blood vessel growth, or find a 'cousin' of nicotine that produces the same effect with fewer problems.

Then again, maybe I should quit daydreaming about new treatments and stick to things that are practical and proven. Oh well, Sunday morning is a good time to let the mind wander...

Re: Nicotine promotes new blood vessel growth

john h on 7/01/01 at 11:44 (051992)

only in canada could this happen wendy.

Re: Nicotine promotes new blood vessel growth

wendyn on 7/01/01 at 22:28 (052017)

Trust me - to hear this guy and his wife tell the story while sitting around at a barbeque with a few beers - it was positively priceless. Had us practically rolling on the floor with his description of how relieved he was when he found the patch and realized that he wasn't likely having a heart attack like he'd first thought. I think they actually had to call poison control or the hospital...that's an awful lot of nicotine for a non-smoker.

Seriously though Brian - who knows? Maybe there is something to it...nicotine is a drug - and although it's harmful the way people use it today..who's to say that there isn't an alternative use for it that could actually be beneficial? Wasn't heroin originally developed as the 'safer' pain medication alternative to morphine? Just because a drug is misused in a way that's harmful - doesn't necessarily mean it's a bad drug. Thalidomide did unspeakable damage to unborn babies, but now they've found it really helps in the treatment of leprosy. Viagra was originally used as a heart medication (can you imagine being the first guy trying to explain the 'unusual' or 'unexpected' side effects to the doctor?

Re: Nicotine promotes new blood vessel growth

john h on 7/02/01 at 08:27 (052041)

This nicotine patch story will certainly give a lot of vindictive wifes a new tool to torment their poor husbands with.

Re: Nicotine and PF

Ryan G. on 7/04/01 at 10:51 (052200)

This is very surprising to me because I found this site after having intense foot pain and talking to a physical therapist friend. The intersting part is that I am quitting nicotine, and the foot pain has come on recently. I am 27, and not overweight (145 pounds), although I did spend a lot of time walking barefoot or in flat leather sandals on hardwood floors. But I am interested in the nicotine connection. And as someone who is quitting nicotine, if anyone is thinking of trying nicotine as a treatment, I would classify that as a very bad idea. Anyone else have a similar connection between heel pain and nicotine?

Re: Nicotine and PF

wendyn on 7/04/01 at 13:48 (052220)

Ryan - I'm not a doctor - but I'd be almost willing to bet money that your foot pain is because of all your walking in bad shoes. You're probably walking more while you're trying to kick the habit. If you haven't already done so - get some really good running shoes for those walks, and avoid going barefoot even at home.

I quit smoking just over 6 years ago, best thing I've ever done. Give me clear lungs and energy any day - even if I have to put up with sore feet.

Re: Nicotine promotes new blood vessel growth

wendyn on 7/01/01 at 11:14 (051989)

Hmmm Brian - this is news to me.

If a non-smoker applies a nicotine patch - there would be some profound physical side effects.

Tell you a little story...

A woman I know had recently quit smoking. She was using the strongest patch (admistered equivalent of about a pack a day nicotine.)

One night her husband (a non smoker) woke up in a cold sweat, his pulse was racing, heart was pounding - he could hardly breathe and he was itchy. Eventually he located the source of his problem - found that the patch had somehow come off the wife in the night and he had rolled onto it - sticking it to his back.

Re: Nicotine promotes new blood vessel growth

BrianJ on 7/01/01 at 11:37 (051991)

Interesting story, Wendy.

I must agree that nicotine would have side effects and would be potentially addictive. My ignorance of nicotine in particular and pharmacology in general prevents me from addressing the issue very well. Perhaps there is a way to isolate the agent that promotes blood vessel growth, or find a 'cousin' of nicotine that produces the same effect with fewer problems.

Then again, maybe I should quit daydreaming about new treatments and stick to things that are practical and proven. Oh well, Sunday morning is a good time to let the mind wander...

Re: Nicotine promotes new blood vessel growth

john h on 7/01/01 at 11:44 (051992)

only in canada could this happen wendy.

Re: Nicotine promotes new blood vessel growth

wendyn on 7/01/01 at 22:28 (052017)

Trust me - to hear this guy and his wife tell the story while sitting around at a barbeque with a few beers - it was positively priceless. Had us practically rolling on the floor with his description of how relieved he was when he found the patch and realized that he wasn't likely having a heart attack like he'd first thought. I think they actually had to call poison control or the hospital...that's an awful lot of nicotine for a non-smoker.

Seriously though Brian - who knows? Maybe there is something to it...nicotine is a drug - and although it's harmful the way people use it today..who's to say that there isn't an alternative use for it that could actually be beneficial? Wasn't heroin originally developed as the 'safer' pain medication alternative to morphine? Just because a drug is misused in a way that's harmful - doesn't necessarily mean it's a bad drug. Thalidomide did unspeakable damage to unborn babies, but now they've found it really helps in the treatment of leprosy. Viagra was originally used as a heart medication (can you imagine being the first guy trying to explain the 'unusual' or 'unexpected' side effects to the doctor?

Re: Nicotine promotes new blood vessel growth

john h on 7/02/01 at 08:27 (052041)

This nicotine patch story will certainly give a lot of vindictive wifes a new tool to torment their poor husbands with.

Re: Nicotine and PF

Ryan G. on 7/04/01 at 10:51 (052200)

This is very surprising to me because I found this site after having intense foot pain and talking to a physical therapist friend. The intersting part is that I am quitting nicotine, and the foot pain has come on recently. I am 27, and not overweight (145 pounds), although I did spend a lot of time walking barefoot or in flat leather sandals on hardwood floors. But I am interested in the nicotine connection. And as someone who is quitting nicotine, if anyone is thinking of trying nicotine as a treatment, I would classify that as a very bad idea. Anyone else have a similar connection between heel pain and nicotine?

Re: Nicotine and PF

wendyn on 7/04/01 at 13:48 (052220)

Ryan - I'm not a doctor - but I'd be almost willing to bet money that your foot pain is because of all your walking in bad shoes. You're probably walking more while you're trying to kick the habit. If you haven't already done so - get some really good running shoes for those walks, and avoid going barefoot even at home.

I quit smoking just over 6 years ago, best thing I've ever done. Give me clear lungs and energy any day - even if I have to put up with sore feet.