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celebrex & vioxx

Posted by john h on 8/21/01 at 19:16 (057477)

On the national news tonight it was reported that JAMA (i think was the source) reported that people taking vioxx and celebrex had a 50% increase in chance of stroke and heart attacks. Merck is disputing the studies but i suggest those of you who are taking these drugs consult with your physician and check the latest info at reliable sources on the internet. I like many of you tried them but they did not help so i discontinued. there are millions of people with arthritis who take them daily.

Re: celebrex & vioxx

Paula G. on 8/21/01 at 21:04 (057488)

I have heard things about these medications too. Thanks.

Re: celebrex & vioxx

wendyn on 8/22/01 at 00:04 (057497)

It can take several years for all the side effects of new drugs are known. How many of us took aspirin when we were sick with the flu as children?

Re: celebrex & vioxx

john h on 8/22/01 at 07:19 (057517)

the 50% increased rate of heart attack and stroke from a prestegious medical journal should get anyone's attention. of course i just heard the lead story and the all the data and facts were not out there. i would suspect that any damage would be very reversable if one quit taking the drug as i think it had to do with blood thining or something to do with the platelets. I would immediately ask my doctor about the continued use. These drugs are an anti-inflamatory with the special ability to reduce the chance of bleeding in the stomach. I think, at least in my case, that one pill a day is all that is required. For many arthritis sufferers who were taking 8-12 aspirin a day it was in somecases a godsend. as i said Merck is disputing the study. I think i took one month of celebrex and one month of vioxx and neither provided me with any relief. i would bet that Dotors will be very reluctant to prescribe these drugs until all the facts are known and FDA weighs in.

Re: Vioxx

BrianG on 8/22/01 at 09:37 (057533)

You know John, I think I could use a good heart attack, probably take my mind off my heel pain !!! I take Vioxx once a day, the maximum recommended dosage. If I stop posting, you'll know why! I'm going to stay with it, unless my doc shuts me off.

BCG

Re: Vioxx

ellen w on 8/22/01 at 10:00 (057538)

I'm still pretty happy with Mobic. Like Celebrex and Vioxx, it's a once a day pill. However, it has a different mechanism of action -- doesn't target the Cox-2 inhibitors, so hopefully, it's also not screwing up my other systems. This could be a catch-22 situation. If these drugs allow you to exercise because of lowered pain, presumably, you are lowering your chances of heart attack and stroke. If you are a couch potato because of pain, than your chances of heart and stroke should be increased. Once again, consumers are left wondering what to do.
ellen

Re: Vioxx

Tammie on 8/22/01 at 10:19 (057541)

Hubby takes both of thease meds, alternating on ocasion, he has Rhum. Arthritis and has used them for years in addition to many other treatments and meds. since he had a history of deep vein thrombosis they include a asprin a day also but I believe it is a lower strenghth then the regular. If it was not for thease types of medications he would have no life at all , He sees a wonderful specialist who does blood work often for liver fuction and of coarse other things often ,He and his Dr. believe in the risks for any and all medications over a period of time but if used wisley and watched with testing they can be a miracle in itself as it allows people to live a life that some could not without the medication as most have a risk if taken long term and not monitored by a Dr. So I am thankful for them for him in any case.

Re: Question for Tammie

Beverly on 8/22/01 at 13:02 (057555)

Tammie,

I didn't know it was ok to mix asperin with Vioxx. Does your husband's doctor have him space out those two drugs? I take Vioxx off and on.
Sometimes I think it helps. Sometimes I'm not sure. Your husband sounds like he suffers as much or more than we do. It must help to have a spouse who understands your plight.
Thanks,
Beverly

Re: Question for Tammie

Tammie on 8/22/01 at 15:29 (057574)

Beverly,Please he is not a dr. and neither am I lol, so can not tell u what or how to do things! For him he includes a 81 mg asprin every day to his meds,He only takes the vioxx or celebrex when his flare ups are bad and the other drugs he takes lol arent enough he takes methatrexate and arava and of course folic acid lol and others lol previcid and gee could go on and on but you get the idea, he has just come of remicade infusions as they seem to not be doing as well as some of the other treatments so he is always changing as his body does. The dr. told him it was fine to include the asprin as long as he didnt use it for pain or more then the one tab a day and the lower dose. As remember he had the dvt which he could not stay on coumiden forever,and this si how they treated him for that .Lol He has a pharmacy of his own , Right now he is not using vioxx or celebrex his stomache is getting a break or a rest as it along with all other meds play havic,and the vioxx or celebrex they say have to build up in system for effect, so he prefers Ibroprofin as it is quicker to help. They change him on and off his system tends to get used to the meds so they change or break for a bit and try something different. Yes he deals with great pain, not every day but several, he works on and keeps going. So it is not easy to have a hubby or spouse who has pain lol as he thinks rest is not good , u need to keep moving and work out the pain not sit and suffer. It is different in ways, and he has several cortisone shots in a year I could not believe how much they give for his condition I always worry for him but the Dr. assures us it is ok he gets them in his back and he has bad knees and nad hip and shoulders lol I could write a book but u see what I mean. He is a pretty good guy but he like me is inpatient . Well If I were you I would ask the dr. if u are concerned and see what he tells u, I am sure he will adress your concerns,we are under impression that for vioxx to work you have to continue it to have it build up it is not instant relief and that if u do not u do not get max effect but again I urge u to check with your doc as he goes to a Rhum specialist and they do different things then our familiy doc did or my pod even. But they do blood work very frequently he always looks like a pin cushion after his visits lol.Good luck to u!

Re: celebrex & vioxx

Barbara TX on 8/22/01 at 19:27 (057614)

Read that in the Wall Street Journal too. Yesterday was my last day of that stuff. It's just not worth it to worry about a heart attack. they even called into question the fact that C & V cut the risk of intestinal problems at all.

Back to straight scotch, I guess. B.

Re: celebrex & vioxx

john h on 8/22/01 at 20:35 (057621)

barb: you can switch to the scotch i am moving to straight V.O.

Re: Question for Tammie

Kathy G on 8/23/01 at 10:06 (057664)

Beverly,

I also take Vioxx daily along with a low-dose aspirin. I take the aspirin because it has many healthy benefits, ie; reduces the threat of heart atack, colon cancer, etc. It actually says in the literature with Vioxx that it is acceptable to take the low-dose aspririn with the Vioxx. One report that I heard about the Vioxx/stroke risk study that was just released said that there was no risk if, in fact, one took the aspirin in conjunction with the Vioxx. Until the study is released in depth, so that we can see how exactly it was done, I'm staying on Vioxx and don't intend to worry about it.

Re: celebrex & vioxx

Paula G. on 8/21/01 at 21:04 (057488)

I have heard things about these medications too. Thanks.

Re: celebrex & vioxx

wendyn on 8/22/01 at 00:04 (057497)

It can take several years for all the side effects of new drugs are known. How many of us took aspirin when we were sick with the flu as children?

Re: celebrex & vioxx

john h on 8/22/01 at 07:19 (057517)

the 50% increased rate of heart attack and stroke from a prestegious medical journal should get anyone's attention. of course i just heard the lead story and the all the data and facts were not out there. i would suspect that any damage would be very reversable if one quit taking the drug as i think it had to do with blood thining or something to do with the platelets. I would immediately ask my doctor about the continued use. These drugs are an anti-inflamatory with the special ability to reduce the chance of bleeding in the stomach. I think, at least in my case, that one pill a day is all that is required. For many arthritis sufferers who were taking 8-12 aspirin a day it was in somecases a godsend. as i said Merck is disputing the study. I think i took one month of celebrex and one month of vioxx and neither provided me with any relief. i would bet that Dotors will be very reluctant to prescribe these drugs until all the facts are known and FDA weighs in.

Re: Vioxx

BrianG on 8/22/01 at 09:37 (057533)

You know John, I think I could use a good heart attack, probably take my mind off my heel pain !!! I take Vioxx once a day, the maximum recommended dosage. If I stop posting, you'll know why! I'm going to stay with it, unless my doc shuts me off.

BCG

Re: Vioxx

ellen w on 8/22/01 at 10:00 (057538)

I'm still pretty happy with Mobic. Like Celebrex and Vioxx, it's a once a day pill. However, it has a different mechanism of action -- doesn't target the Cox-2 inhibitors, so hopefully, it's also not screwing up my other systems. This could be a catch-22 situation. If these drugs allow you to exercise because of lowered pain, presumably, you are lowering your chances of heart attack and stroke. If you are a couch potato because of pain, than your chances of heart and stroke should be increased. Once again, consumers are left wondering what to do.
ellen

Re: Vioxx

Tammie on 8/22/01 at 10:19 (057541)

Hubby takes both of thease meds, alternating on ocasion, he has Rhum. Arthritis and has used them for years in addition to many other treatments and meds. since he had a history of deep vein thrombosis they include a asprin a day also but I believe it is a lower strenghth then the regular. If it was not for thease types of medications he would have no life at all , He sees a wonderful specialist who does blood work often for liver fuction and of coarse other things often ,He and his Dr. believe in the risks for any and all medications over a period of time but if used wisley and watched with testing they can be a miracle in itself as it allows people to live a life that some could not without the medication as most have a risk if taken long term and not monitored by a Dr. So I am thankful for them for him in any case.

Re: Question for Tammie

Beverly on 8/22/01 at 13:02 (057555)

Tammie,

I didn't know it was ok to mix asperin with Vioxx. Does your husband's doctor have him space out those two drugs? I take Vioxx off and on.
Sometimes I think it helps. Sometimes I'm not sure. Your husband sounds like he suffers as much or more than we do. It must help to have a spouse who understands your plight.
Thanks,
Beverly

Re: Question for Tammie

Tammie on 8/22/01 at 15:29 (057574)

Beverly,Please he is not a dr. and neither am I lol, so can not tell u what or how to do things! For him he includes a 81 mg asprin every day to his meds,He only takes the vioxx or celebrex when his flare ups are bad and the other drugs he takes lol arent enough he takes methatrexate and arava and of course folic acid lol and others lol previcid and gee could go on and on but you get the idea, he has just come of remicade infusions as they seem to not be doing as well as some of the other treatments so he is always changing as his body does. The dr. told him it was fine to include the asprin as long as he didnt use it for pain or more then the one tab a day and the lower dose. As remember he had the dvt which he could not stay on coumiden forever,and this si how they treated him for that .Lol He has a pharmacy of his own , Right now he is not using vioxx or celebrex his stomache is getting a break or a rest as it along with all other meds play havic,and the vioxx or celebrex they say have to build up in system for effect, so he prefers Ibroprofin as it is quicker to help. They change him on and off his system tends to get used to the meds so they change or break for a bit and try something different. Yes he deals with great pain, not every day but several, he works on and keeps going. So it is not easy to have a hubby or spouse who has pain lol as he thinks rest is not good , u need to keep moving and work out the pain not sit and suffer. It is different in ways, and he has several cortisone shots in a year I could not believe how much they give for his condition I always worry for him but the Dr. assures us it is ok he gets them in his back and he has bad knees and nad hip and shoulders lol I could write a book but u see what I mean. He is a pretty good guy but he like me is inpatient . Well If I were you I would ask the dr. if u are concerned and see what he tells u, I am sure he will adress your concerns,we are under impression that for vioxx to work you have to continue it to have it build up it is not instant relief and that if u do not u do not get max effect but again I urge u to check with your doc as he goes to a Rhum specialist and they do different things then our familiy doc did or my pod even. But they do blood work very frequently he always looks like a pin cushion after his visits lol.Good luck to u!

Re: celebrex & vioxx

Barbara TX on 8/22/01 at 19:27 (057614)

Read that in the Wall Street Journal too. Yesterday was my last day of that stuff. It's just not worth it to worry about a heart attack. they even called into question the fact that C & V cut the risk of intestinal problems at all.

Back to straight scotch, I guess. B.

Re: celebrex & vioxx

john h on 8/22/01 at 20:35 (057621)

barb: you can switch to the scotch i am moving to straight V.O.

Re: Question for Tammie

Kathy G on 8/23/01 at 10:06 (057664)

Beverly,

I also take Vioxx daily along with a low-dose aspirin. I take the aspirin because it has many healthy benefits, ie; reduces the threat of heart atack, colon cancer, etc. It actually says in the literature with Vioxx that it is acceptable to take the low-dose aspririn with the Vioxx. One report that I heard about the Vioxx/stroke risk study that was just released said that there was no risk if, in fact, one took the aspirin in conjunction with the Vioxx. Until the study is released in depth, so that we can see how exactly it was done, I'm staying on Vioxx and don't intend to worry about it.